According to a study of Cambridge scientist hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of people who are overweight and people with obesity when compared to people who are a healthy weight.
According to the Office for Health Improvement and Disparities, almost two-thirds of adults in the UK are overweight or living with obesity.
Dr Stephanie Brown, from the Department of Psychiatry at the University of Cambridge, said: "Although we know the hypothalamus is important for determining how much we eat, we actually have very little direct information about this brain region in living humans, That's because it is very small and hard to make out on traditional MRI brain scans."
To circumvent this, Dr Brown and colleagues used a machine learning-based algorithm to analyse MRI brain scans from 1,351 young adults with a range of BMI scores. They were looking for variations in the hypothalamus when comparing people who are underweight, healthy weight, overweight, and obese.
the team discovered that young adults who were overweight or obese had significantly larger hypothalamus overall volumes. In fact, the team discovered a strong correlation between the hypothalamus’ volume and body mass index (BMI).
While the exact significance of the finding is unclear, one explanation is that the change relates to inflammation.
The further deep research for the hypothalamus l is going on.
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